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Search Results for " fm 381 "

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Compounds

Cat No. Product Name Synonyms Targets
T5091 FM-381 FM381 JAK
FM381 is a potent covalent reversible inhibitor of JAK3. FM-381 has an IC50 of 127 pM for JAK3, with 410, 2700 and 3600-fold selectivity over JAK1, JAK2 and TYK2, respectively.
T22333 FM-479 Others
FM-479, an FM-381 structural analog, exhibits no inhibitory potency against JAK3 or other kinases when used at the FM-381 effective dosing range (100-300 nM). FM-479 is used as a negative control for FM-381.
T31832 FM-476
FM-476 is a negative control for FM-381.
TargetMol